• 師資陣容

    • 行政技術人員

葉伯壽 Bak-Sau Yip 合聘教授
  • 國立清華大學生物技術研究所博士

經歷

1.臺大醫院新竹分院部主任
‧臺大醫院新竹分院神經部醫師
‧國立交通大學資工系合聘助理教授
2.國立清華大學清大通識中心助理教授

研究興趣

分子生物、藥物設計

研究計畫

1.104年衛生福利部長照資源不足地區建置失智症社區服務計畫--優等
2.104科技部計畫:Tau蛋白正子掃描像在偵測輕度認知功能障礙及阿茲海默症預測能力之前瞻性研究
3.104科技部計畫:認知功能衰退之流行病探討:心臟及腦血流動力學與短長期營養調控機制研究--遠期和近期營養及化學不平衡狀況對於老人大腦認知功能的影響: 「營養過盛」、「營養不良」、及代謝異常所扮演的角色
4.103科技部計畫計:腦血管硬化與血流動力學對認知功能的影響
5.103科技部計畫:微型核醣體對心腦交互作用及大腦認知功能的調控與分子機轉

代表著作

2016
1. Real-world evaluation of compliance and preference in Alzheimer's disease treatment: an observational study in Taiwan.
Patient Prefer Adherence
Patient Prefer Adherence 2016 30;10:383-90. Epub 2016 Mar 30.
Tzu-Hsien Lai, Wen-Fu Wang, Bak-Sau Yip, Yu-Wan Yang, Giia-Sheun Peng, Shih-Jei Tsai, Yi-Chu Liao, Ming-Chyi Pai
Division of Behavioral Neurology, Department of Neurology, College of Medicine, National Cheng Kung University, Tainan City, Taiwan; Alzheimer's Disease Research Center, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan City, Taiwan.

2015
2. Ultrashort Antimicrobial Peptides with Antiendotoxin Properties.
Antimicrob. Agents Chemother.
Antimicrob Agents Chemother 2015 Aug 1;59(8):5052-6. Epub 2015 Jun 1.
Ya-Han Chih, Yen-Shan Lin, Bak-Sau Yip, Hsiu-Ju Wei, Hung-Lun Chu, Hui-Yuan Yu, Hsi-Tsung Cheng, Yu-Ting Chou, Jya-Wei Cheng
Institute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu, Taiwan ytchou@life.nthu.edu.tw jwcheng@life.nthu.edu.tw.

3. Novel antimicrobial peptides with high anticancer activity and selectivity.
PLoS One 2015 13;10(5):e0126390. Epub 2015 May 13.
Hung-Lun Chu, Bak-Sau Yip, Kuan-Hao Chen, Hui-Yuan Yu, Ya-Han Chih, Hsi-Tsung Cheng, Yu-Ting Chou, Jya-Wei Cheng
4. Potential antitumor therapeutic application of Grimontia hollisae thermostable direct hemolysin mutants.
Cancer Sci 2015 Apr 10;106(4):447-54. Epub 2015 Mar 10.
Sheng-Cih Huang, Yu-Kuo Wang, Wan-Ting Huang, Tsam-Ming Kuo, Bak-Sau Yip, Tien-Hsiung Thomas Li, Tung-Kung Wu
5. Carotid artery stenting improves cerebral hemodynamics regardless of the flow direction of ophthalmic artery.
Angiology 2015 Feb 24;66(2):180-6. Epub 2014 Feb 24.
Chi-Hung Liu, Chien-Hung Chang, Ting-Yu Chang, Kuo-Lun Huang, Jr-Rung Lin, Yu-Wei Chen, Bak-Sau Yip, Shan-Jin Ryu, Yeu-Jhy Chang, Tsong-Hai Lee
2014
6.Impact of Coexisting Coronary Artery Disease on the Occurrence of Cerebral Ischemic Lesions after Carotid Stenting Published: April 14, 2014DOI: 10.1371/journal.pone.0094280 (SCI) Kuo-Lun Huang, Yeu-Jhy Chang, Chien-Hung Chang,Ting-Yu Chang, Chi-Hung Liu, I-Chang Hsieh, Ho-Fai Wong, Yau-Yau Wai, Yu-Wei Chen, Bak-Sau Yip,
7. Carotid Artery Stenting Improves Cerebral Hemodynamics Regardless of the Flow Direction of Ophthalmic Artery. Angiology 2014 Feb 24. Epub 2014 Feb 24. (SCI) Chi-Hung Liu, Chien-Hung Chang, Ting-Yu Chang, Kuo-Lun Huang, Jr-Rung Lin,Yu-Wei Chen, Bak-Sau Yip, Shan-Jin Ryu, Yeu-Jhy Chang, Tsong-Hai Lee
2013
8. Proteinuria independently predicts unfavorable outcome of ischemic stroke patients receiving intravenous thrombolysis.PLoS ON 2013 22;8(11):e80527.Epub 2013 Nov 22. 2013Feb (SCI) Chih-Hao Chen, Sung-Chun Tang, Li-Kai Tsai, Shin-Joe Yeh, Kai-Hsiang Chen, Chen-Hua Li, Yu-Jen Hsiao, Yu-Wei Chen, Bak-Sau Yip, Jiann-Shing Jeng
9. The thermostable direct hemolysin from Grimontia hollisae causes acute hepatotoxicity in vitro and in vivo.PLoS One 2013 21;8(2):e56226. Epub 2013 Feb 21. (SCI) Yan-Ren Lin, Yao-Li Chen, Keh-Bin Wang, Yi-Fang Wu, Yu-Kuo Wang, Sheng-Cih Huang, Tzu-An Liu, Manoswini Nayak, Bak-Sau Yip, Tung-Kung Wu
10. Boosting Salt Resistance of Short Antimicrobial Peptides Antimicrobial Agents and Chemotherapy p. 4050–4052 August 2013 Volume 57 Number ( SCI) Hung-Lun Chu,a Hui-Yuan Yu,a Bak-Sau Yip,a,b Ya-Han Chih,a Chong-Wen Liang,a Hsi-Tsung Cheng,a Jya-Wei Chenga
11.Correlations between membrane immersion depth, orientation and salt-resistance of tryptophan-rich antimicrobial peptides, Biochimica et Biophysica Acta 1828 (2013) 2720–2728
(SCI) Hui-Yuan Yu a,1, Bak-Sau Yip a,b,1, Chih-Hsiang Tu a, Heng-Li Chena, Hung-Lun Chua, Ya-Han Chiha, Hsi-Tsung Cheng a, Shih-Che Sue c, Jya-Wei Cheng a